Polr1b - RNA polymerase I subunit B Gene

Rattus norvegicus

Also known as RPA2; Rpo1-2

Gene ID: 83582 | Gene type: protein coding

About Polr1b

Summary

Contributes to DNA-directed 5'-3' RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr1b Products(1)

mRNA	Protein	Name
NM_031773.2	NP_113961.2	DNA-directed RNA polymerase I subunit RPA2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
contributes to DNA-directed 5'-3' RNA polymerase activity	IDA IDA: Inferred from direct assay	9422795	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in rRNA transcription	IDA IDA: Inferred from direct assay	9422795	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of RNA polymerase I complex	IDA IDA: Inferred from direct assay	9422795	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

DNA-directed RNA polymerase I subunit RPA2

A127	RNA polymerase 1-2
RNA polymerase I (127 kDa subunit)	RNA polymerase I polypeptide B
RNA polymerase I subunit 2	RPA135
polymerase (RNA) I polypeptide B	polymerase (RNA) I subunit B

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10838	POLR1B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21910	Polr1b Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Polr1b	NCBI	NCBI:84172

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