Polr1b - RNA polymerase I subunit B Gene

Also Known as RPA2; Rpo1-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83582

Summary

Contributes to DNA-directed 5'-3' RNA polymerase activity. Involved in rRNA transcription. Part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr1b Products (1)

mRNA Protein Name
NM_031773.2 NP_113961.2 DNA-directed RNA polymerase I subunit RPA2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA-directed 5'-3' RNA polymerase activity IDA
IDA: Inferred from direct assay
9422795 RGD
Biological Process GO Annotation Evidence References Source
involved in rRNA transcription IDA
IDA: Inferred from direct assay
9422795 RGD
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
9422795 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase I subunit RPA2

  • A127

  • RNA polymerase 1-2

  • RNA polymerase I (127 kDa subunit)

  • RNA polymerase I polypeptide B

  • RNA polymerase I subunit 2

  • RPA135

  • polymerase (RNA) I polypeptide B

  • polymerase (RNA) I subunit B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10838 POLR1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21910 Polr1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1b NCBI NCBI:84172