Usf1 - upstream transcription factor 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83586

Summary

Enables DNA binding activity; DNA-binding transcription factor activity; and identical protein binding activity. Contributes to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in glucose metabolic process and positive regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in cardiovascular system disease and type 2 diabetes mellitus. Orthologous to human USF1 (upstream transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Usf1 Products (1)

mRNA Protein Name
NM_031777.3 NP_113965.1 upstream stimulatory factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12200434 RGD
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12200434 RGD
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
17408383 RGD
contributes to DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17408383 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
17408383 RGD
enables identical protein binding IMP
IMP: Inferred from mutant phenotype
8576131 RGD
enables protein-containing complex binding IMP
IMP: Inferred from mutant phenotype
8576131 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17408383 RGD
Biological Process GO Annotation Evidence References Source
involved in glucose metabolic process IDA
IDA: Inferred from direct assay
12200434 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15557322 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17408383 RGD
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12200434 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

upstream stimulatory factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15513 USF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19651 Usf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26144 Usf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usf1 NCBI NCBI:7391