Bicc1 - BicC family RNA binding protein 1 Gene

Also Known as bpk; jcpk; Bic-C

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83675

Summary

Predicted to enable RNA binding activity. Acts upstream of or within determination of left/right symmetry; heart development; and kidney development. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; embryo mesenchyme; gonad; intraembryonic coelom; and sensory organ. Used to study autosomal dominant polycystic kidney disease; autosomal recessive polycystic kidney disease; cystic kidney disease; and visceral heterotaxy. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Orthologous to human BICC1 (BicC family RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Bicc1 Products (2)

mRNA Protein Name
NM_001347189.1 NP_001334118.1 protein bicaudal C homolog 1 isoform 2
NM_031397.3 NP_113574.1 protein bicaudal C homolog 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25671767 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
27002738 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein bicaudal C homolog 1

  • bicaudal C homolog 1

  • juvenile congenital polycystic kidney disease

  • polycystic kidney mutation of BALB/c origin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01497 BICC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21499 Bicc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28017 Bicc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bicc1 NCBI NCBI:80114