Dbr1 - debranching RNA lariats 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83703

Summary

Enables RNA lariat debranching enzyme activity. Acts upstream of or within mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and skin. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human DBR1 (debranching RNA lariats 1). [provided by Alliance of Genome Resources, Apr 2022]

Dbr1 Products (2)

mRNA Protein Name
NM_001368298.1 NP_001355227.1 lariat debranching enzyme isoform 2
NM_031403.3 NP_113580.2 lariat debranching enzyme isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA lariat debranching enzyme activity IDA
IDA: Inferred from direct assay
10982890 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
10982890 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lariat debranching enzyme

  • debranching enzyme homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156744 DBr-1 Degrader 98.87% Unkown
HY-RS03553 DBR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dbr1 NCBI NCBI:51163