Slc26a5 - solute carrier family 26 member 5 Gene

Also Known as Pres; prestin

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83819

Summary

Enables identical protein binding activity. Involved in several processes, including chloride transmembrane transport; cochlea development; and response to ischemia. Located in basolateral plasma membrane; cytoplasm; and lateral plasma membrane. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61. Orthologous to human SLC26A5 (solute carrier family 26 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc26a5 Products (1)

mRNA Protein Name
NM_030840.1 NP_110467.1 prestin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chloride:bicarbonate antiporter activity IDA
IDA: Inferred from direct assay
22890707 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
17998209 RGD
Biological Process GO Annotation Evidence References Source
involved in bicarbonate transport IDA
IDA: Inferred from direct assay
22890707 RGD
involved in chloride transmembrane transport IMP
IMP: Inferred from mutant phenotype
11423665 RGD
involved in chloride transport IDA
IDA: Inferred from direct assay
22890707 RGD
involved in cochlea development IEP
IEP: Inferred from expression pattern
20006695 RGD
involved in fructose transmembrane transport IDA
IDA: Inferred from direct assay
12938672 RGD
involved in monoatomic anion transmembrane transport IDA
IDA: Inferred from direct assay
22063625 RGD
involved in monoatomic ion transmembrane transport IDA
IDA: Inferred from direct assay
11274441 RGD
involved in negative regulation of monoatomic ion transmembrane transport IDA
IDA: Inferred from direct assay
15660259 RGD
involved in oxalate transport IDA
IDA: Inferred from direct assay
24710176 RGD
involved in positive regulation of cell motility IDA
IDA: Inferred from direct assay
11274441 RGD
involved in positive regulation of cell size IDA
IDA: Inferred from direct assay
12938672 RGD
involved in response to auditory stimulus IEP
IEP: Inferred from expression pattern
17005342 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
15925203 RGD
involved in response to potassium ion IEP
IEP: Inferred from expression pattern
21624428 RGD
involved in response to salicylic acid IEP
IEP: Inferred from expression pattern
19173110 RGD
involved in response to salt IEP
IEP: Inferred from expression pattern
21624428 RGD
involved in response to thyroid hormone IEP
IEP: Inferred from expression pattern
11867734 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
20006695 RGD
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
20525072 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
11867734 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prestin

  • prestin (motor protein)

  • solute carrier family 26 (anion exchanger), member 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13139 SLC26A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc26a5 NCBI NCBI:375611