2. Gene
  3. Gpr137b - G protein-coupled receptor 137B Gene

Gpr137b - G protein-coupled receptor 137B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tm7sf1; D13Abb1e; C730041E01

Gene ID: 83924 | Gene type: protein coding

About Gpr137b

Summary

Involved in negative regulation of bone resorption; negative regulation of osteoclast differentiation; and regulation of macrophage activation. Located in lysosomal membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Orthologous to human GPR137B (G protein-coupled receptor 137B). [provided by Alliance of Genome Resources, Apr 2022]

Gpr137b Products(1)

mRNA Protein Name
NM_031999.2 NP_114388.2 integral membrane protein GPR137B
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
31173907 MGI
involved in negative regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
31173907 MGI
involved in regulation of macrophage activation IMP
IMP: Inferred from mutant phenotype
30595385 MGI
Cellular Component GO Annotation Evidence Reference Source
located in lysosomal membrane IMP
IMP: Inferred from mutant phenotype
31173907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integral membrane protein GPR137B

transmembrane 7 superfamily member 1 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05659 GPR137B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr137b NCBI NCBI:7107