2. Gene
  3. Nrtn - neurturin Gene

Nrtn - neurturin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 84423 | Gene type: protein coding

About Nrtn

Summary

Enables growth factor activity. Predicted to act upstream of or within nervous system development; neural crest cell migration; and transmembrane receptor protein tyrosine kinase signaling pathway. Located in axon. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human NRTN (Neurturin). [provided by Alliance of Genome Resources, Apr 2022]

Nrtn Products(1)

mRNA Protein Name
NM_053399.1 NP_445851.1 neurturin precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables growth factor activity IDA
IDA: Inferred from direct assay
10719212 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
16841166 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurturin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09582 NRTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18488 Nrtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24970 Nrtn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrtn NCBI NCBI:4902
Mus musculus Nrtn NCBI NCBI:18188