Stau1 - staufen double-stranded RNA binding protein 1 Gene

Rattus norvegicus

Also known as Stau

Gene ID: 84496 | Gene type: protein coding

About Stau1

Summary

Enables double-stranded RNA binding activity and protein Phosphatase 1 binding activity. Involved in cellular response to oxidative stress; modification of postsynaptic structure; and positive regulation of long-term synaptic potentiation. Located in cytoplasm; neuron projection; and neuronal cell body. Is active in glutamatergic synapse. Orthologous to human STAU1 (staufen double-stranded RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Stau1 Products(2)

mRNA	Protein	Name
NM_001109907.1	NP_001103377.1	double-stranded RNA-binding protein Staufen homolog 1 isoform 2
NM_053436.2	NP_445888.1	double-stranded RNA-binding protein Staufen homolog 1 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables double-stranded RNA binding	IDA IDA: Inferred from direct assay	11145988	RGD
enables protein phosphatase 1 binding	IPI IPI: Inferred from physical interaction	12065664	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to oxidative stress	IEP IEP: Inferred from expression pattern	15525674	RGD
involved in modification of postsynaptic structure	IDA IDA: Inferred from direct assay	21635779	RGD
involved in modification of postsynaptic structure	IMP IMP: Inferred from mutant phenotype	21635779	RGD
involved in modulation of chemical synaptic transmission	IDA IDA: Inferred from direct assay	21635779	RGD
involved in modulation of chemical synaptic transmission	IMP IMP: Inferred from mutant phenotype	21635779	RGD
involved in positive regulation of long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	21508097	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	21635779	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	21635779	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	12065664	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

double-stranded RNA-binding protein Staufen homolog 1

staufen RNA binding protein homolog 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13900	STAU1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Stau1	NCBI	NCBI:6780

Name
Email *

	Sorry, but the email address you supplied was invalid.