Stau1 - staufen double-stranded RNA binding protein 1 Gene

Also Known as Stau

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84496

Summary

Enables double-stranded RNA binding activity and protein Phosphatase 1 binding activity. Involved in cellular response to oxidative stress; modification of postsynaptic structure; and positive regulation of long-term synaptic potentiation. Located in cytoplasm; neuron projection; and neuronal cell body. Is active in glutamatergic synapse. Orthologous to human STAU1 (staufen double-stranded RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Stau1 Products (2)

mRNA Protein Name
NM_001109907.1 NP_001103377.1 double-stranded RNA-binding protein Staufen homolog 1 isoform 2
NM_053436.2 NP_445888.1 double-stranded RNA-binding protein Staufen homolog 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables double-stranded RNA binding IDA
IDA: Inferred from direct assay
11145988 RGD
enables protein phosphatase 1 binding IPI
IPI: Inferred from physical interaction
12065664 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to oxidative stress IEP
IEP: Inferred from expression pattern
15525674 RGD
involved in modification of postsynaptic structure IDA
IDA: Inferred from direct assay
21635779 RGD
involved in modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
21635779 RGD
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
21635779 RGD
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
21635779 RGD
involved in positive regulation of long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
21508097 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21635779 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21635779 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
12065664 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

double-stranded RNA-binding protein Staufen homolog 1

  • staufen RNA binding protein homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13900 STAU1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stau1 NCBI NCBI:6780