Rims1 - regulating synaptic membrane exocytosis 1 Gene

Also Known as Rim1; RIM1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84556

Summary

Enables SH3 domain binding activity; protein kinase binding activity; and small GTPase binding activity. Involved in long-term synaptic potentiation; positive regulation of inhibitory postsynaptic potential; and positive regulation of synaptic vesicle priming. Located in presynaptic membrane. Is active in glutamatergic synapse and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1). [provided by Alliance of Genome Resources, Apr 2022]

Rims1 Products (2)

mRNA Protein Name
NM_001398595.1 NP_001385524.1 regulating synaptic membrane exocytosis protein 1 isoform 1
NM_052829.3 NP_439894.2 regulating synaptic membrane exocytosis protein 1 isoform 2
Protein Preferred Names Protein Names

regulating synaptic membrane exocytosis protein 1

  • RIM 1

  • Rab3 effector

  • Rim1b protein

  • rab-3-interacting molecule 1

  • rab3-interacting molecule 1

Rims1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rims1 Q9JIR4 Cacna1a Rattus norvegicus P54282
Y2H
21241895
Intra
Rims1 Q9JIR4 Erc1 Rattus norvegicus Q811U3
NMR
16095618
Intra
Rims1 Q9JIR4 Erc1 Rattus norvegicus Q811U3
ITC
16095618
Intra
Rims1 Q9JIR4 Erc1 Rattus norvegicus Q811U3
Pull Down
12391317
Intra
Rims1 Q9JIR4 Cacna1a Rattus norvegicus O70368
NMR
21241895
Intra
Rims1 Q9JIR4 Cacna1b Rattus norvegicus O89089
NMR
21241895
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D1751 RIM-1 / Unkown
HY-RS11978 RIMS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rims1 NCBI NCBI:22999