Rims1 - regulating synaptic membrane exocytosis 1 Gene

Rattus norvegicus

Also known as Rim1; RIM1a

Gene ID: 84556 | Gene type: protein coding

About Rims1

Summary

Enables SH3 domain binding activity; protein kinase binding activity; and small GTPase binding activity. Involved in long-term synaptic potentiation; positive regulation of inhibitory postsynaptic potential; and positive regulation of synaptic vesicle priming. Located in presynaptic membrane. Is active in glutamatergic synapse and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in cone-rod dystrophy 7. Orthologous to human RIMS1 (regulating synaptic membrane exocytosis 1). [provided by Alliance of Genome Resources, Apr 2022]

Rims1 Products(2)

mRNA	Protein	Name
NM_001398595.1	NP_001385524.1	regulating synaptic membrane exocytosis protein 1 isoform 1
NM_052829.3	NP_439894.2	regulating synaptic membrane exocytosis protein 1 isoform 2

Protein Preferred Names

Protein Names

regulating synaptic membrane exocytosis protein 1

RIM 1	Rab3 effector
Rim1b protein	rab-3-interacting molecule 1
rab3-interacting molecule 1

Rims1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Rims1	Q9JIR4	Cacna1a	Rattus norvegicus	P54282	Y2H	21241895
Intra	Rims1	Q9JIR4	Erc1	Rattus norvegicus	Q811U3	NMR	16095618
Intra	Rims1	Q9JIR4	Erc1	Rattus norvegicus	Q811U3	ITC	16095618
Intra	Rims1	Q9JIR4	Erc1	Rattus norvegicus	Q811U3	Pull Down	12391317
Intra	Rims1	Q9JIR4	Cacna1a	Rattus norvegicus	O70368	NMR	21241895
Intra	Rims1	Q9JIR4	Cacna1b	Rattus norvegicus	O89089	NMR	21241895

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-D1751	RIM-1		/	Unkown
HY-RS11978	RIMS1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rims1	NCBI	NCBI:22999

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