TPST1 - tyrosylprotein sulfotransferase 1 Gene

Homo sapiens

Also known as TANGO13A

Gene ID: 8460 | Gene type: protein coding

About TPST1

Cytogenetic location: 7q11.21 Genomic coordinates (GRCh38): 7:66,198,790-66,360,443 (from NCBI)

This gene has 6 transcripts (splice variants), 206 orthologues and 1 paralogue. Broad expression in gall bladder (RPKM 13.2), urinary bladder (RPKM 9.5) and 22 other tissues.

Summary

Enables protein homodimerization activity and protein-tyrosine sulfotransferase activity. Involved in peptidyl-tyrosine sulfation. Is integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

TPST1 Products(1)

mRNA	Protein	Name
NM_003596.4	NP_003587.1	protein-tyrosine sulfotransferase 1

TPST1 Protein Structure

Sulfotransfer_3

0
100
200
300
370 a.a.

Protein Preferred Names

Protein Names

protein-tyrosine sulfotransferase 1

TPST-1

Recombinant TPST1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77255	TPST1 Protein, Human (HEK293, His)	O60507 (Q26-E370)	≥95%

Related Diseases

Diseases

Alias

Lung Carcinoma In Situ

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14954	TPST1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TPST1	VGNC	VGNC:36264
Felis catus	TPST1	VGNC	VGNC:66487
Mus musculus	TPST1	MGD	MGI:1298231
Macaca mulatta	TPST1	VGNC	VGNC:78638
Rattus norvegicus	TPST1	RGD	RGD:1308473
Canis familiaris	TPST1	VGNC	VGNC:47755
Others	TPST1	NCBI

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