Prdx4 - peroxiredoxin 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85274

Summary

Predicted to enable identical protein binding activity and thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis; hydrogen peroxide catabolic process; and response to oxidative stress. Predicted to act upstream of or within several processes, including negative regulation of male germ cell proliferation; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; and protein maturation by protein folding. Located in extracellular space and smooth endoplasmic reticulum. Orthologous to human PRDX4 (peroxiredoxin 4). [provided by Alliance of Genome Resources, Apr 2022]

Prdx4 Products (1)

mRNA Protein Name
NM_053512.2 NP_445964.1 peroxiredoxin-4 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10025941 RGD
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
22665516 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxiredoxin-4

  • antioxidant enzyme AOE372

  • peroxiredoxin IV

  • prx-IV

  • thioredoxin peroxidase AO372

  • thioredoxin-dependent peroxide reductase A0372

  • thioredoxin-dependent peroxiredoxin 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18834 Prdx4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11077 PRDX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25326 Prdx4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdx4 NCBI NCBI:10549