2. Gene
  3. PRDX4 - peroxiredoxin 4 Gene

PRDX4 - peroxiredoxin 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PRX-4; AOE372; AOE37-2; HEL-S-97n

Gene ID: 10549 | Gene type: protein coding

About PRDX4

Cytogenetic location: Xp22.11 Genomic coordinates (GRCh38): X:23,667,493-23,686,397 (from NCBI)

This gene has 5 transcripts (splice variants), 212 orthologues and 4 paralogues. Ubiquitous expression in pancreas (RPKM 49.0), liver (RPKM 22.7) and 25 other tissues.

Summary

The protein encoded by this gene is an antioxidant Enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]

PRDX4 Products(1)

mRNA Protein Name
NM_006406.2 NP_006397.1 peroxiredoxin-4 precursor

PRDX4 Protein Structure

AhpC-TSA

AhpC-TSA: AhpC/TSA family (82 - 213)

1-cysPrx_C

1-cysPrx_C: C-terminal domain of 1-Cys peroxiredoxin (234 - 264)

  • 0
  • 100
  • 200
  • 271 a.a.
Protein Preferred Names Protein Names

peroxiredoxin-4

antioxidant enzyme AOE372

Recombinant PRDX4 Proteins

Cat. No. Product Name Accession Purity
HY-P71232 PRDX4 Protein, Human (His) Q13162 (W38-N271) ≥95%

Related Diseases

Diseases Alias
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
Filariasis

Disease Due To Superfamily Filarioidea

Bancroftian Filarial Fever

Mumu

Wanganga

Bancroftian Filariasis

Wuchereriosis

Brugiosis

Malayan Filariasis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11077 PRDX4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PRDX4 VGNC VGNC:64347
Macaca mulatta PRDX4 VGNC VGNC:76272
Bos taurus PRDX4 VGNC VGNC:33302
Rattus norvegicus PRDX4 RGD RGD:620043
Canis familiaris PRDX4 VGNC VGNC:44952
Mus musculus PRDX4 MGD MGI:1859815
Others PRDX4 NCBI