2. Gene
  3. LIN7A - Lin7a lin-7 homolog A, crumbs cell polarity complex component Gene

LIN7A - Lin7a lin-7 homolog A, crumbs cell polarity complex component Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Veli1; MALS-1; lin-7-Ba

Gene ID: 85327 | Gene type: protein coding

About LIN7A

Summary

Enables PDZ domain binding activity. Predicted to be involved in maintenance of epithelial cell apical/basal polarity; neurotransmitter secretion; and protein localization to basolateral plasma membrane. Predicted to act upstream of or within inner ear development and synaptic vesicle transport. Located in basolateral plasma membrane. Is active in synapse. Orthologous to human LIN7A (lin-7 homolog A, crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]

LIN7A Products(1)

mRNA Protein Name
NM_001408921.1 NP_001395850.1 protein lin-7 homolog A
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
15024025 RGD
Cellular Component GO Annotation Evidence Reference Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
10710551 RGD
is active in synapse IDA
IDA: Inferred from direct assay
10341223 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lin-7 homolog A

mammalian lin-seven protein 1

protein lin-7 homolog A-like

veli-1 protein

vertebrate lin-7 homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07676 LIN7A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens LIN7A NCBI NCBI:8825