Angpt1 - angiopoietin 1 Gene

Also Known as Agpt; Agpt1; Ang-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 89807

Summary

Enables identical protein binding activity. Involved in several processes, including animal organ development; response to estrogen; and response to vitamin B3. Located in extracellular space. Biomarker of gastric ulcer; in situ carcinoma; myocardial infarction; nephrosis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Orthologous to human ANGPT1 (angiopoietin 1). [provided by Alliance of Genome Resources, Apr 2022]

Angpt1 Products (1)

mRNA Protein Name
NM_053546.2 NP_445998.2 angiopoietin-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
15056293 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
16437624 RGD
involved in glomerulus vasculature development IMP
IMP: Inferred from mutant phenotype
20056745 RGD
involved in liver regeneration IEP
IEP: Inferred from expression pattern
11549276 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17989359 RGD
involved in ovarian follicle development IMP
IMP: Inferred from mutant phenotype
17989359 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
15637314 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
11129953 RGD
involved in response to vitamin B3 IEP
IEP: Inferred from expression pattern
17557352 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15056293 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-1

Recombinant Angpt1 Proteins

Cat. No. Product Name Accession Purity
HY-P700560 ANGPT1/Angiopoietin-1, Rat (P. pastoris, His) O35460 (S20-F497) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117733 Zerumin A Inhibitor / Unkown
HY-RS00687 ANGPT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17668 Angpt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24129 Angpt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angpt1 NCBI NCBI:284