SPOCD1 - SPOC domain containing 1 Gene

Also Known as PPP1R146

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 90853

About SPOCD1

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:31,790,422-31,816,022 (from NCBI)

This gene has 14 transcripts (splice variants), 93 orthologues and 2 paralogues. Biased expression in testis (RPKM 4.6), urinary bladder (RPKM 3.3) and 7 other tissues.

Summary

This gene encodes a protein that belongs to the TFIIS family of transcription factors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

SPOCD1 Products (6)

mRNA Protein Name
NM_001281987.3 NP_001268916.1 SPOC domain-containing protein 1 isoform 2
NM_001281988.3 NP_001268917.1 SPOC domain-containing protein 1 isoform 3
NM_001394397.1 NP_001381326.1 SPOC domain-containing protein 1 isoform 4
NM_001394398.1 NP_001381327.1 SPOC domain-containing protein 1 isoform 5
NM_001394399.1 NP_001381328.1 SPOC domain-containing protein 1 isoform 6
NM_144569.7 NP_653170.3 SPOC domain-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
38359823 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPOCD1 Protein Structure

TFIIS_M

TFIIS_M: Transcription factor S-II (TFIIS), central domain (608 - 718)

SPOC

SPOC: SPOC domain (867 - 963)

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  • 1216 a.a.
Protein Preferred Names Protein Names

SPOC domain-containing protein 1

  • protein phosphatase 1, regulatory subunit 146

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13694 SPOCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SPOCD1 VGNC VGNC:56150
Felis catus SPOCD1 VGNC VGNC:107633
Rattus norvegicus SPOCD1 RGD RGD:1560989
Macaca mulatta SPOCD1 VGNC VGNC:77997
Canis familiaris SPOCD1 VGNC VGNC:84433
Mus musculus SPOCD1 MGD MGI:3652045
Others SPOCD1 NCBI