CHURC1 - churchill domain containing 1 Gene

Also Known as chch; My015; C14orf52

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 91612

About CHURC1

Cytogenetic location: 14q23.3 Genomic coordinates (GRCh38): 14:64,914,455-64,935,368 (from NCBI)

This gene has 8 transcripts (splice variants) and 175 orthologues. Ubiquitous expression in fat (RPKM 18.1), brain (RPKM 17.2) and 25 other tissues.

Summary

Predicted to enable zinc ion binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. [provided by Alliance of Genome Resources, Apr 2022]

CHURC1 Products (3)

mRNA Protein Name
NM_001204064.2 NP_001190993.2 protein Churchill isoform 3
NM_001386928.1 NP_001373857.1 protein Churchill isoform 2
NM_145165.4 NP_660148.4 protein Churchill isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHURC1 Protein Structure

Churchill

Churchill: Churchill protein (28 - 139)

  • 0
  • 100
  • 139 a.a.
Protein Preferred Names Protein Names

protein Churchill

CHURC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CHURC1 Q8WUH1 ZNF581 Homo sapiens Q9P0T4
Y2H Prey Pooling
32296183
Intra
CHURC1 Q8WUH1 ZNF581 Homo sapiens Q9P0T4
Validated Y2H
32296183
Intra
CHURC1 Q8WUH1 ZNF581 Homo sapiens Q9P0T4
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Gastrojejunal Ulcer

  • Acute Gastrojejunal Ulcer With Hemorrhage

  • Acute Gastrojejunal Ulcer With Hemorrhage And Obstruction

  • Acute Gastrojejunal Ulcer With Hemorrhage And Perforation

  • Acute Gastrojejunal Ulcer With Hemorrhage And Perforation, With Obstruction

  • Acute Gastrojejunal Ulcer With Hemorrhage, With Perforation And With Obstruction

  • Acute Gastrojejunal Ulcer With Perforation

  • Acute Gastrojejunal Ulcer With Perforation And Obstruction

  • Acute Gastrojejunal Ulcer With Perforation, With Obstruction

  • Acute Gastrojejunal Ulcer Without Hemorrhage And Without Perforation

  • Acute Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction

  • Acute Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction

  • Acute Gastrojejunal Ulcer, With Hemorrhage, With Obstruction

  • Chronic Gastrojejunal Ulcer Without Hemorrhage And Without Perforation

  • Chronic Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction

  • Chronic Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction

  • Marginal Ulcer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02701 CHURC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CHURC1 VGNC VGNC:27355
Rattus norvegicus CHURC1 RGD RGD:1305116
Canis familiaris CHURC1 VGNC VGNC:39262
Mus musculus CHURC1 MGD MGI:1923684
Others CHURC1 NCBI