Tac4 - tachykinin 4 Gene

Also Known as PPT-C

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93670

Summary

Enables receptor ligand activity; substance K receptor binding activity; and substance P receptor binding activity. Involved in positive regulation of cytosolic calcium ion concentration. Acts upstream of or within positive regulation of saliva secretion and tachykinin receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; mammary gland; skin; spleen; and stomach. Orthologous to human TAC4 (tachykinin precursor 4). [provided by Alliance of Genome Resources, Apr 2022]

Tac4 Products (1)

mRNA Protein Name
NM_053093.2 NP_444323.1 tachykinin-4 preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables receptor ligand activity IDA
IDA: Inferred from direct assay
12716968 MGI
enables signaling receptor binding IDA
IDA: Inferred from direct assay
11062498 MGI
enables substance K receptor binding IPI
IPI: Inferred from physical interaction
12716968 MGI
enables substance P receptor binding IPI
IPI: Inferred from physical interaction
12716968 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12716968 MGI
acts upstream of or within positive regulation of saliva secretion IDA
IDA: Inferred from direct assay
11062498 MGI
acts upstream of or within tachykinin receptor signaling pathway IDA
IDA: Inferred from direct assay
11062498 MGI
involved in tachykinin receptor signaling pathway IDA
IDA: Inferred from direct assay
12716968 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tachykinin-4

  • hemokinin I (HK-1)

  • preprotachykinin-C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14138 TAC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tac4 NCBI NCBI:255061