2. Gene
  3. P2rx5 - purinergic receptor P2X, ligand-gated ion channel, 5 Gene

P2rx5 - purinergic receptor P2X, ligand-gated ion channel, 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P2X5

Gene ID: 94045 | Gene type: protein coding

About P2rx5

Summary

Enables extracellularly ATP-gated cation channel activity. Predicted to be involved in several processes, including positive regulation of calcium ion import across plasma membrane; regulation of skeletal muscle tissue regeneration; and response to ATP. Predicted to act upstream of or within cell surface receptor signaling pathway. Predicted to be located in cytosol and plasma membrane. Predicted to be integral component of nuclear inner membrane. Is expressed in several structures, including forelimb bud; nervous system; neural ectoderm; olfactory epithelium; and retina. Orthologous to human P2RX5 (purinergic receptor P2X 5). [provided by Alliance of Genome Resources, Apr 2022]

P2rx5 Products(3)

mRNA Protein Name
NM_001376982.1 NP_001363911.1 P2X purinoceptor 5 isoform 2
NM_001376983.1 NP_001363912.1 P2X purinoceptor 5 isoform 3
NM_033321.4 NP_201578.2 P2X purinoceptor 5 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables extracellularly ATP-gated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
11404011 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

P2X purinoceptor 5

purinergic receptor P2X5-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09909 P2RX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx5 NCBI NCBI:5026