Trim6 - tripartite motif-containing 6 Gene

Also Known as D7Ertd684e; C430046K18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94088

Summary

Enables DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of type I interferon-mediated signaling pathway; and regulation of gene expression. Located in cytosol and nucleus. Is expressed in testis. Orthologous to human TRIM6 (tripartite motif containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Trim6 Products (1)

mRNA Protein Name
NM_001013616.2 NP_001013637.1 tripartite motif-containing protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
22328504 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11331580 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
24882218 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to virus IDA
IDA: Inferred from direct assay
24882218 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
22328504 MGI
involved in negative regulation of stem cell differentiation IMP
IMP: Inferred from mutant phenotype
22328504 MGI
involved in negative regulation of viral genome replication IMP
IMP: Inferred from mutant phenotype
24882218 MGI
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22328504 MGI
involved in positive regulation of type I interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
24882218 MGI
involved in protein polyubiquitination IDA
IDA: Inferred from direct assay
22328504 MGI
NOT involved in regulation of protein stability IMP
IMP: Inferred from mutant phenotype
22328504 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11331580 MGI
located in cytosol IMP
IMP: Inferred from mutant phenotype
22328504 MGI
located in nucleus IMP
IMP: Inferred from mutant phenotype
22328504 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tripartite motif-containing protein 6

  • RING-type E3 ubiquitin transferase TRIM6

  • tripartite motif protein 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15060 TRIM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim6 NCBI NCBI:117854