Trim11 - tripartite motif-containing 11 Gene

Mus musculus

Gene ID: 94091 | Gene type: protein coding

About Trim11

Summary

Enables protein domain specific binding activity and ubiquitin protein Ligase activity. Involved in several processes, including defense response to Other organism; negative regulation of viral transcription; and regulation of viral entry into host cell. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; liver; nervous system; and urinary system. Orthologous to human TRIM11 (tripartite motif containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Trim11 Products(2)

mRNA	Protein	Name
NM_001290988.1	NP_001277917.1	E3 ubiquitin-protein ligase TRIM11 isoform 1
NM_053168.2	NP_444398.1	E3 ubiquitin-protein ligase TRIM11 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16098226	MGI
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	16098226	MGI
enables transcription factor binding	IPI IPI: Inferred from physical interaction	18628401	MGI
enables ubiquitin protein ligase activity	IDA IDA: Inferred from direct assay	18574153	MGI
enables ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	18628401	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in innate immune response	IDA IDA: Inferred from direct assay	18248090	MGI
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	18628401	MGI
involved in negative regulation of neurogenesis	IMP IMP: Inferred from mutant phenotype	18628401	MGI
involved in negative regulation of viral entry into host cell	IDA IDA: Inferred from direct assay	18248090	MGI
involved in negative regulation of viral transcription	IDA IDA: Inferred from direct assay	18248090	MGI
involved in positive regulation of viral entry into host cell	IDA IDA: Inferred from direct assay	18248090	MGI
involved in suppression of viral release by host	IDA IDA: Inferred from direct assay	18248090	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	11331580	MGI
located in nucleus	IDA IDA: Inferred from direct assay	11331580	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

E3 ubiquitin-protein ligase TRIM11

RING-type E3 ubiquitin transferase TRIM11

tripartite motif-containing protein 11

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15020	TRIM11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trim11	NCBI	NCBI:81559

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