Trim11 - tripartite motif-containing 11 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94091

Summary

Enables protein domain specific binding activity and ubiquitin protein Ligase activity. Involved in several processes, including defense response to Other organism; negative regulation of viral transcription; and regulation of viral entry into host cell. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; liver; nervous system; and urinary system. Orthologous to human TRIM11 (tripartite motif containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Trim11 Products (2)

mRNA Protein Name
NM_001290988.1 NP_001277917.1 E3 ubiquitin-protein ligase TRIM11 isoform 1
NM_053168.2 NP_444398.1 E3 ubiquitin-protein ligase TRIM11 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16098226 MGI
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
16098226 MGI
enables transcription factor binding IPI
IPI: Inferred from physical interaction
18628401 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
18574153 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
18628401 MGI
Biological Process GO Annotation Evidence References Source
involved in innate immune response IDA
IDA: Inferred from direct assay
18248090 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
18628401 MGI
involved in negative regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
18628401 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
18248090 MGI
involved in negative regulation of viral transcription IDA
IDA: Inferred from direct assay
18248090 MGI
involved in positive regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
18248090 MGI
involved in suppression of viral release by host IDA
IDA: Inferred from direct assay
18248090 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11331580 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11331580 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM11

  • RING-type E3 ubiquitin transferase TRIM11

  • tripartite motif-containing protein 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15020 TRIM11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim11 NCBI NCBI:81559