CABIN1 - Cabin1 calcineurin binding protein 1 Gene

Rattus norvegicus

Also known as Cain

Gene ID: 94165 | Gene type: protein coding

About CABIN1

Summary

Enables protein domain specific binding activity and protein Phosphatase 2B binding activity. Involved in negative regulation of cell death and response to activity. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CABIN1 (Calcineurin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

CABIN1 Products(1)

mRNA	Protein	Name
NM_053575.2	NP_446027.2	calcineurin-binding protein cabin-1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	10931822	RGD
enables protein domain specific binding	IMP IMP: Inferred from mutant phenotype	12114545	RGD
enables protein phosphatase 2B binding	IDA IDA: Inferred from direct assay	9660798	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	12114545	RGD
involved in response to activity	IEP IEP: Inferred from expression pattern	16266368	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

calcineurin-binding protein cabin-1

calcineurin inhibitor

calcineurin-binding protein cabin-1-like

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01780	CABIN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CABIN1	NCBI	NCBI:23523

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