Col4a6 - collagen, type IV, alpha 6 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94216

Summary

An extracellular matrix structural constituent. Acts upstream of or within cellular response to amino acid stimulus; collagen-activated tyrosine kinase receptor signaling pathway; and extracellular matrix organization. Located in basement membrane. Part of Collagen type IV trimer. Is expressed in several structures, including bone; meninges; oral region epithelium; sensory organ; and trunk. Human ortholog(s) of this gene implicated in AMME complex and X-linked deafness 6. Orthologous to human COL4A6 (Collagen type IV alpha 6 chain). [provided by Alliance of Genome Resources, Apr 2022]

Col4a6 Products (1)

mRNA Protein Name
NM_053185.2 NP_444415.2 collagen alpha-6(IV) chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables extracellular matrix structural constituent IDA
IDA: Inferred from direct assay
10965041 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to amino acid stimulus IDA
IDA: Inferred from direct assay
20548288 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IGI
IGI: Inferred from genetic interaction
10970885 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
10965041 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
10534397 MGI
part of collagen type IV trimer IDA
IDA: Inferred from direct assay
10965041 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen alpha-6(IV) chain

  • procollagen, type IV, alpha 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0444 Rubiadin 99.20% Unkown
HY-RS02988 COL4A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Col4a6 NCBI NCBI:1288