Cnnm2 - cyclin M2 Gene

Also Known as Clp2; Acdp2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94219

Summary

Enables ATP binding activity and magnesium ion transmembrane transporter activity. Acts upstream of or within magnesium ion transport. Located in basolateral plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and retina. Human ortholog(s) of this gene implicated in renal hypomagnesemia 6. Orthologous to human CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnnm2 Products (2)

mRNA Protein Name
NM_001102471.1 NP_001095941.1 metal transporter CNNM2 isoform b
NM_033569.3 NP_291047.2 metal transporter CNNM2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
24706765 MGI
enables magnesium ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
24706765 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within magnesium ion transport IDA
IDA: Inferred from direct assay
21397062 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
21397062 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24706765 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metal transporter CNNM2

  • ancient conserved domain protein 2

  • ancient conserved domain-containing protein 2

  • cyclin-like protein 2

  • mACDP2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02896 CNNM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnnm2 NCBI NCBI:54805