Cnnm4 - cyclin M4 Gene

Also Known as Acdp4; 5430430O18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94220

Summary

Enables magnesium ion transmembrane transporter activity and sodium ion transmembrane transporter activity. Acts upstream of or within enamel mineralization; magnesium ion homeostasis; and magnesium ion transport. Located in basolateral plasma membrane. Is expressed in colon and metanephros. Human ortholog(s) of this gene implicated in Jalili syndrome. Orthologous to human CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4). [provided by Alliance of Genome Resources, Apr 2022]

Cnnm4 Products (1)

mRNA Protein Name
NM_033570.2 NP_291048.2 metal transporter CNNM4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables magnesium ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
24339795 MGI
enables sodium ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
24339795 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within enamel mineralization IMP
IMP: Inferred from mutant phenotype
24339795 MGI
acts upstream of or within magnesium ion homeostasis IMP
IMP: Inferred from mutant phenotype
24339795 MGI
acts upstream of or within magnesium ion transport IMP
IMP: Inferred from mutant phenotype
24339795 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
24339795 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metal transporter CNNM4

  • ancient conserved domain protein 4

  • ancient conserved domain-containing protein 4

  • mACDP4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W043170 PRL3-CNNM4 PPI-IN-1 Inhibitor 99.33% Unkown
HY-RS02898 CNNM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20384 Cnnm4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26894 Cnnm4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnnm4 NCBI NCBI:26504