Olig3 - oligodendrocyte transcription factor 3 Gene

Also Known as Bhlhb7; oligo3; bHLHe20

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94222

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future hindbrain; genitourinary system; inner ear; and skeletal muscle. Orthologous to human OLIG3 (oligodendrocyte transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Olig3 Products (1)

mRNA Protein Name
NM_053008.3 NP_443734.2 oligodendrocyte transcription factor 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15769945 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
15769945 MGI
acts upstream of or within spinal cord motor neuron cell fate specification IMP
IMP: Inferred from mutant phenotype
15769945 MGI
acts upstream of or within spinal cord motor neuron differentiation IGI
IGI: Inferred from genetic interaction
15674731 MGI
acts upstream of or within spinal cord motor neuron differentiation IMP
IMP: Inferred from mutant phenotype
15769945 MGI
acts upstream of or within spinal cord motor neuron migration IMP
IMP: Inferred from mutant phenotype
15769945 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oligodendrocyte transcription factor 3

  • basic helix-loop-helix domain-containing class B protein 7

  • oligodendrocyte-specific bHLH transcription factor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09779 OLIG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Olig3 NCBI NCBI:167826