Slc4a10 - solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 Gene

Also Known as NCBE; mKIAA4136

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94229

Summary

Enables anion:anion antiporter activity and sodium:bicarbonate symporter activity. Involved in regulation of short-term neuronal synaptic plasticity and visual perception. Acts upstream of or within several processes, including brain development; locomotory exploration behavior; and regulation of cellular pH. Located in several cellular components, including basolateral plasma membrane; dendrite; and neuronal cell body. Is expressed in several structures, including gut; nervous system; sensory organ; and testis. Orthologous to human SLC4A10 (solute carrier family 4 member 10). [provided by Alliance of Genome Resources, Apr 2022]

Slc4a10 Products (13)

mRNA Protein Name
NM_001242378.1 NP_001229307.1 sodium-driven chloride bicarbonate exchanger isoform 1
NM_001242379.1 NP_001229308.1 sodium-driven chloride bicarbonate exchanger isoform 3
NM_001242380.1 NP_001229309.1 sodium-driven chloride bicarbonate exchanger isoform 4
NM_001242381.1 NP_001229310.1 sodium-driven chloride bicarbonate exchanger isoform 5
NM_001242382.1 NP_001229311.1 sodium-driven chloride bicarbonate exchanger isoform 6
NM_001242383.1 NP_001229312.1 sodium-driven chloride bicarbonate exchanger isoform 7
NM_001362671.1 NP_001349600.1 sodium-driven chloride bicarbonate exchanger isoform 8
NM_001362672.1 NP_001349601.1 sodium-driven chloride bicarbonate exchanger isoform 9
NM_001362673.1 NP_001349602.1 sodium-driven chloride bicarbonate exchanger isoform 10
NM_001362674.1 NP_001349603.1 sodium-driven chloride bicarbonate exchanger isoform 11
NM_001362675.1 NP_001349604.1 sodium-driven chloride bicarbonate exchanger isoform 12
NM_001362676.1 NP_001349605.1 sodium-driven chloride bicarbonate exchanger isoform 13
NM_033552.3 NP_291030.2 sodium-driven chloride bicarbonate exchanger isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sodium,bicarbonate:chloride antiporter activity IDA
IDA: Inferred from direct assay
10993873 MGI
enables sodium:bicarbonate symporter activity IDA
IDA: Inferred from direct assay
20566632 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain morphogenesis IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within locomotory exploration behavior IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within proton transmembrane transport IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within pyramidal neuron development IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within regulation of cellular pH IMP
IMP: Inferred from mutant phenotype
18165320 MGI
acts upstream of or within regulation of pH IDA
IDA: Inferred from direct assay
10993873 MGI
involved in regulation of short-term neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
26136660 MGI
acts upstream of or within response to light stimulus IMP
IMP: Inferred from mutant phenotype
18165320 MGI
involved in visual perception IMP
IMP: Inferred from mutant phenotype
23056253 MGI
Cellular Component GO Annotation Evidence References Source
located in CA3 pyramidal cell dendrite IDA
IDA: Inferred from direct assay
18165320 MGI
located in GABA-ergic synapse IDA
IDA: Inferred from direct assay
37459438 MGI
located in apical dendrite IDA
IDA: Inferred from direct assay
18165320 MGI
located in axon terminus IDA
IDA: Inferred from direct assay
23056253 MGI
located in basal dendrite IDA
IDA: Inferred from direct assay
18165320 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
14592810 MGI
located in dendrite IDA
IDA: Inferred from direct assay
23056253 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
18165320 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
23500099 MGI
located in somatodendritic compartment IDA
IDA: Inferred from direct assay
24905082 MGI
located in synapse IDA
IDA: Inferred from direct assay
26136660 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-driven chloride bicarbonate exchanger

  • sodium bicarbonate cotransporter NBCn2-E

  • sodium bicarbonate cotransporter member 10 variant NBCn2-E'

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13266 SLC4A10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc4a10 NCBI NCBI:57282