Clic5 - chloride intracellular channel 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 94272

Summary

Enables Chloride Channel activity. Predicted to be involved in chloride transport and sensory perception of sound. Predicted to act upstream of or within several processes, including auditory receptor cell stereocilium organization; diet induced thermogenesis; and neuromuscular process controlling balance. Located in stereocilium bundle. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Orthologous to human CLIC5 (chloride intracellular channel 5). [provided by Alliance of Genome Resources, Apr 2022]

Clic5 Products (1)

mRNA Protein Name
NM_053603.4 NP_446055.1 chloride intracellular channel protein 5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chloride channel activity IDA
IDA: Inferred from direct assay
8537381 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
24285636 RGD
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
26777142 RGD
located in stereocilium base IDA
IDA: Inferred from direct assay
24285636 RGD
located in stereocilium bundle IDA
IDA: Inferred from direct assay
17021174 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chloride intracellular channel protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02807 CLIC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20382 Clic5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26892 Clic5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clic5 NCBI NCBI:53405