Mfsd6 - major facilitator superfamily domain containing 6 Gene

Also Known as MMR2; 2210010L05Rik; 9630025I22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 98682

Summary

Enables MHC class I protein binding activity and MHC class I receptor activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I. Located in plasma membrane. Orthologous to human MFSD6 (major facilitator superfamily domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Mfsd6 Products (5)

mRNA Protein Name
NM_001357464.2 NP_001344393.1 major facilitator superfamily domain-containing protein 6 isoform 3
NM_001403607.1 NP_001390536.1 major facilitator superfamily domain-containing protein 6 isoform 3
NM_001403611.1 NP_001390540.1 major facilitator superfamily domain-containing protein 6 isoform 1
NM_133829.3 NP_598590.2 major facilitator superfamily domain-containing protein 6 isoform 1
NM_178081.5 NP_835182.1 major facilitator superfamily domain-containing protein 6 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables MHC class I protein binding IPI
IPI: Inferred from physical interaction
17010536 MGI
enables MHC class I receptor activity IPI
IPI: Inferred from physical interaction
17010536 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I IDA
IDA: Inferred from direct assay
17010536 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
17010536 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

major facilitator superfamily domain-containing protein 6

  • macrophage MHC class I receptor 2

  • macrophage MHC receptor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08393 MFSD6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfsd6 NCBI NCBI:54842