Eps8l2 - EPS8-like 2 Gene

Also Known as Eps8r2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 98845

Summary

Predicted to enable actin filament binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Involved in sensory perception of sound. Located in stereocilium tip. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 106. Orthologous to human EPS8L2 (EPS8 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Eps8l2 Products (1)

mRNA Protein Name
NM_133191.3 NP_573454.2 epidermal growth factor receptor kinase substrate 8-like protein 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in sensory perception of sound IDA
IDA: Inferred from direct assay
23918390 MGI
Cellular Component GO Annotation Evidence References Source
located in stereocilium bundle IDA
IDA: Inferred from direct assay
23918390 MGI
located in stereocilium tip IDA
IDA: Inferred from direct assay
23918390 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epidermal growth factor receptor kinase substrate 8-like protein 2

  • EPS8 related protein 2

  • EPS8-like protein 2

  • epidermal growth factor receptor pathway substrate 8-like protein 2

  • epidermal growth factor receptor pathway substrate 8-related protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04456 EPS8L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eps8l2 NCBI NCBI:64787