2. Gene
  3. Pomt1 - protein-O-mannosyltransferase 1 Gene

Pomt1 - protein-O-mannosyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 99011 | Gene type: protein coding

About Pomt1

Summary

Predicted to enable mannosyltransferase activity. Acts upstream of or within extracellular matrix organization. Located in acrosomal vesicle and sarcoplasmic reticulum. Is expressed in several structures, including central nervous system; eye; gonad; heart; and hemolymphoid system gland. Used to study muscular dystrophy-dystroglycanopathy. Human ortholog(s) of this gene implicated in cardiomyopathy; cleft lip; lissencephaly; and muscular dystrophy (multiple). Orthologous to human POMT1 (protein O-mannosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pomt1 Products(1)

mRNA Protein Name
NM_145145.2 NP_660127.1 protein O-mannosyl-transferase 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
15383666 MGI
Cellular Component GO Annotation Evidence Reference Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
17456771 MGI
part of dolichyl-phosphate-mannose-protein mannosyltransferase complex IDA
IDA: Inferred from direct assay
18490429 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
17456771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein O-mannosyl-transferase 1

dolichyl-phosphate-mannose--protein mannosyltransferase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10870 POMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pomt1 NCBI NCBI:10585