2. Gene
  3. Adgrl2 - adhesion G protein-coupled receptor L2 Gene

Adgrl2 - adhesion G protein-coupled receptor L2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lec1; Gm619; Lphh1; Lphn2; CIRL-2; mKIAA0786

Gene ID: 99633 | Gene type: protein coding

About Adgrl2

Summary

Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Involved in synapse organization. Acts upstream of or within positive regulation of synapse assembly and response to bacterium. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in heart. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2). [provided by Alliance of Genome Resources, Apr 2022]

Adgrl2 Products(29)

mRNA Protein Name
NM_001081298.2 NP_001074767.1 adhesion G protein-coupled receptor L2 isoform 1 precursor
NM_001405986.1 NP_001392915.1 adhesion G protein-coupled receptor L2 isoform 2 precursor
NM_001405987.1 NP_001392916.1 adhesion G protein-coupled receptor L2 isoform 3 precursor
NM_001405988.1 NP_001392917.1 adhesion G protein-coupled receptor L2 isoform 3 precursor
NM_001405989.1 NP_001392918.1 adhesion G protein-coupled receptor L2 isoform 4 precursor
NM_001405990.1 NP_001392919.1 adhesion G protein-coupled receptor L2 isoform 5 precursor
NM_001405991.1 NP_001392920.1 adhesion G protein-coupled receptor L2 isoform 5 precursor
NM_001405992.1 NP_001392921.1 adhesion G protein-coupled receptor L2 isoform 6 precursor
NM_001405993.1 NP_001392922.1 adhesion G protein-coupled receptor L2 isoform 6 precursor
NM_001405994.1 NP_001392923.1 adhesion G protein-coupled receptor L2 isoform 7 precursor
NM_001405995.1 NP_001392924.1 adhesion G protein-coupled receptor L2 isoform 8 precursor
NM_001405996.1 NP_001392925.1 adhesion G protein-coupled receptor L2 isoform 8 precursor
NM_001405997.1 NP_001392926.1 adhesion G protein-coupled receptor L2 isoform 8 precursor
NM_001405998.1 NP_001392927.1 adhesion G protein-coupled receptor L2 isoform 9 precursor
NM_001405999.1 NP_001392928.1 adhesion G protein-coupled receptor L2 isoform 10 precursor
NM_001406000.1 NP_001392929.1 adhesion G protein-coupled receptor L2 isoform 10 precursor
NM_001406001.1 NP_001392930.1 adhesion G protein-coupled receptor L2 isoform 10 precursor
NM_001406002.1 NP_001392931.1 adhesion G protein-coupled receptor L2 isoform 10 precursor
NM_001406003.1 NP_001392932.1 adhesion G protein-coupled receptor L2 isoform 11 precursor
NM_001406004.1 NP_001392933.1 adhesion G protein-coupled receptor L2 isoform 12 precursor
NM_001406005.1 NP_001392934.1 adhesion G protein-coupled receptor L2 isoform 13 precursor
NM_001406006.1 NP_001392935.1 adhesion G protein-coupled receptor L2 isoform 14 precursor
NM_001406007.1 NP_001392936.1 adhesion G protein-coupled receptor L2 isoform 15 precursor
NM_001406008.1 NP_001392937.1 adhesion G protein-coupled receptor L2 isoform 16 precursor
NM_001406009.1 NP_001392938.1 adhesion G protein-coupled receptor L2 isoform 17 precursor
NM_001406010.1 NP_001392939.1 adhesion G protein-coupled receptor L2 isoform 17 precursor
NM_001406011.1 NP_001392940.1 adhesion G protein-coupled receptor L2 isoform 17 precursor
NM_001406018.1 NP_001392947.1 adhesion G protein-coupled receptor L2 isoform 3 precursor
NM_001406019.1 NP_001392948.1 adhesion G protein-coupled receptor L2 isoform 8 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
involved in synapse organization IDA
IDA: Inferred from direct assay
28972101 MGI
involved in synapse organization IMP
IMP: Inferred from mutant phenotype
28972101 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28972101 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28972101 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
28972101 MGI
is active in postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
28972101 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor L2

G protein coupled receptor Lec1

calcium-independent alpha-latrotoxin receptor 2

calcium-independent alpha-latrotoxin receptor homolog 2

latrophilin 1

latrophilin-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00362 ADGRL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrl2 NCBI NCBI:23266