Adgrl2 - adhesion G protein-coupled receptor L2 Gene
Also Known as Lec1; Gm619; Lphh1; Lphn2; CIRL-2; mKIAA0786
Species: Mus musculus
Gene Type: protein coding
Gene ID: 99633
Summary
Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Involved in synapse organization. Acts upstream of or within positive regulation of synapse assembly and response to bacterium. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in heart. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2). [provided by Alliance of Genome Resources, Apr 2022]
Adgrl2 Products (29)
| mRNA | Protein | Name |
|---|---|---|
| NM_001081298.2 | NP_001074767.1 | adhesion G protein-coupled receptor L2 isoform 1 precursor |
| NM_001405986.1 | NP_001392915.1 | adhesion G protein-coupled receptor L2 isoform 2 precursor |
| NM_001405987.1 | NP_001392916.1 | adhesion G protein-coupled receptor L2 isoform 3 precursor |
| NM_001405988.1 | NP_001392917.1 | adhesion G protein-coupled receptor L2 isoform 3 precursor |
| NM_001405989.1 | NP_001392918.1 | adhesion G protein-coupled receptor L2 isoform 4 precursor |
| NM_001405990.1 | NP_001392919.1 | adhesion G protein-coupled receptor L2 isoform 5 precursor |
| NM_001405991.1 | NP_001392920.1 | adhesion G protein-coupled receptor L2 isoform 5 precursor |
| NM_001405992.1 | NP_001392921.1 | adhesion G protein-coupled receptor L2 isoform 6 precursor |
| NM_001405993.1 | NP_001392922.1 | adhesion G protein-coupled receptor L2 isoform 6 precursor |
| NM_001405994.1 | NP_001392923.1 | adhesion G protein-coupled receptor L2 isoform 7 precursor |
| NM_001405995.1 | NP_001392924.1 | adhesion G protein-coupled receptor L2 isoform 8 precursor |
| NM_001405996.1 | NP_001392925.1 | adhesion G protein-coupled receptor L2 isoform 8 precursor |
| NM_001405997.1 | NP_001392926.1 | adhesion G protein-coupled receptor L2 isoform 8 precursor |
| NM_001405998.1 | NP_001392927.1 | adhesion G protein-coupled receptor L2 isoform 9 precursor |
| NM_001405999.1 | NP_001392928.1 | adhesion G protein-coupled receptor L2 isoform 10 precursor |
| NM_001406000.1 | NP_001392929.1 | adhesion G protein-coupled receptor L2 isoform 10 precursor |
| NM_001406001.1 | NP_001392930.1 | adhesion G protein-coupled receptor L2 isoform 10 precursor |
| NM_001406002.1 | NP_001392931.1 | adhesion G protein-coupled receptor L2 isoform 10 precursor |
| NM_001406003.1 | NP_001392932.1 | adhesion G protein-coupled receptor L2 isoform 11 precursor |
| NM_001406004.1 | NP_001392933.1 | adhesion G protein-coupled receptor L2 isoform 12 precursor |
| NM_001406005.1 | NP_001392934.1 | adhesion G protein-coupled receptor L2 isoform 13 precursor |
| NM_001406006.1 | NP_001392935.1 | adhesion G protein-coupled receptor L2 isoform 14 precursor |
| NM_001406007.1 | NP_001392936.1 | adhesion G protein-coupled receptor L2 isoform 15 precursor |
| NM_001406008.1 | NP_001392937.1 | adhesion G protein-coupled receptor L2 isoform 16 precursor |
| NM_001406009.1 | NP_001392938.1 | adhesion G protein-coupled receptor L2 isoform 17 precursor |
| NM_001406010.1 | NP_001392939.1 | adhesion G protein-coupled receptor L2 isoform 17 precursor |
| NM_001406011.1 | NP_001392940.1 | adhesion G protein-coupled receptor L2 isoform 17 precursor |
| NM_001406018.1 | NP_001392947.1 | adhesion G protein-coupled receptor L2 isoform 3 precursor |
| NM_001406019.1 | NP_001392948.1 | adhesion G protein-coupled receptor L2 isoform 8 precursor |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within positive regulation of synapse assembly |
IDA
IDA: Inferred from direct assay
|
24613359 | MGI |
| acts upstream of or within response to bacterium |
IEP
IEP: Inferred from expression pattern
|
23012479 | MGI |
| involved in synapse organization |
IDA
IDA: Inferred from direct assay
|
28972101 | MGI |
| involved in synapse organization |
IMP
IMP: Inferred from mutant phenotype
|
28972101 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in glutamatergic synapse |
IDA
IDA: Inferred from direct assay
|
28972101 | MGI |
| is active in glutamatergic synapse |
IMP
IMP: Inferred from mutant phenotype
|
28972101 | MGI |
| is active in postsynaptic membrane |
IDA
IDA: Inferred from direct assay
|
28972101 | MGI |
| is active in postsynaptic membrane |
IMP
IMP: Inferred from mutant phenotype
|
28972101 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
adhesion G protein-coupled receptor L2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00362 | ADGRL2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service