1. Metabolic Enzyme/Protease
  2. HIF/HIF Prolyl-Hydroxylase
  3. Izilendustat

Izilendustat 

Cat. No.: HY-44809 Purity: 99.20%
Handling Instructions

Izilendustat is a potent inhibitor of prolyl hydroxylase which can stabilize hypoxia inducible factor- 1 alpha (HIF- lα) and hypoxia inducible factor-2 (HIF-2). Izilendustat has the potential for researching diseases that relate to the body’s inmmune response like colitis and other inflammatory bowel diseases (extracted from patent WO2011057115A1 and WO2011057121A1).

For research use only. We do not sell to patients.

Izilendustat Chemical Structure

Izilendustat Chemical Structure

CAS No. : 1303512-02-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
5 mg USD 64 In-stock
Estimated Time of Arrival: December 31
10 mg USD 104 In-stock
Estimated Time of Arrival: December 31
50 mg USD 288 In-stock
Estimated Time of Arrival: December 31
100 mg USD 464 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Izilendustat:

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Description

Izilendustat is a potent inhibitor of prolyl hydroxylase which can stabilize hypoxia inducible factor- 1 alpha (HIF- lα) and hypoxia inducible factor-2 (HIF-2). Izilendustat has the potential for researching diseases that relate to the body’s inmmune response like colitis and other inflammatory bowel diseases (extracted from patent WO2011057115A1 and WO2011057121A1)[1][1].

Molecular Weight

433.93

Formula

C22H28ClN3O4

CAS No.
SMILES

O=C(N1CCN(CC(C=CN2CC3=CC=C(Cl)C=C3)=C(O)C2=O)CC1)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (57.61 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3045 mL 11.5226 mL 23.0452 mL
5 mM 0.4609 mL 2.3045 mL 4.6090 mL
10 mM 0.2305 mL 1.1523 mL 2.3045 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.20%

References
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Product Name:
Izilendustat
Cat. No.:
HY-44809
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