Cars - cysteinyl-tRNA synthetase Gene

Also Known as CA3; Cars1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27267

Summary

Predicted to enable several functions, including ATP binding activity; cysteine-tRNA Ligase activity; and protein homodimerization activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to act upstream of or within translation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human CARS1 (cysteinyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cars Products (2)

mRNA Protein Name
NM_001252593.1 NP_001239522.1 cysteine--tRNA ligase, cytoplasmic isoform 2
NM_013742.5 NP_038770.3 cysteine--tRNA ligase, cytoplasmic isoform 1
Protein Preferred Names Protein Names

cysteine--tRNA ligase, cytoplasmic

  • cysRS

  • cysteinyl-tRNA synthetase, cytoplasmic

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0488A Vincristine 98.60% Yes
HY-70037 Cinacalcet Agonist 99.93% Yes
HY-70037A Cinacalcet hydrochloride Agonist 99.98% Yes
HY-B0349 Meclizine dihydrochloride 99.95% Unkown
HY-157959 Orphenadrine 99.71% Unkown
HY-B0349A Meclizine / Unkown
HY-B0349B Meclizine dihydrochloride monohydrate / Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159649 BMS-986408 99.35% Phase 2
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99157 Omburtamab Inhibitor 99.16% Phase 2

Pre-clinical Phase

Bioactive Molecules (63)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-163028 ML-T7 99.93% Unkown
HY-103244 CITCO Inducer 99.60% Unkown
HY-103243 TCPOBOP Inhibitor 99.70% Unkown
HY-112171 γ-L-Glutamyl-L-alanine Modulator 98.0% Unkown
HY-119459 Fluopyram 99.76% Unkown
HY-153084A CD19 CAR mRNA (Human) / Unkown
HY-110249 CINPA1 99.80% Unkown
HY-155978A RDN2150 TFA Inhibitor 99.80% Unkown
HY-131911 PROTAC IDO1 Degrader-1 Inhibitor 99.00% Unkown
HY-144987 RBN013209 Inhibitor 98.63% Unkown
HY-148495 Carnosine conjugated hyalyronate Inhibitor 90.0% Unkown
HY-W008583 Bis(4-tert-butylphenyl)amine / Unkown
HY-N1457 Chrysosplenetin 99.84% Unkown
HY-W013854 5α-Androstan-3β-ol 98.00% Unkown
HY-112171R γ-L-Glutamyl-L-alanine (Standard) Modulator 99.29% Unkown
HY-145534 trans-2-Octenoyl-L-carnitine 99.92% Unkown
HY-146231A SS47 TFA Inhibitor 99.88% Unkown
HY-RS01933 CARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W015026 Isobutylparaben 98.87% Unkown
HY-W101305 Fmoc-Pen(Acm)-OH / Unkown
HY-111634 Epsilon-momfluorothrin 99.76% Unkown
HY-15105 SB-423562 Antagonist 99.66% Unkown
HY-155978 RDN2150 Inhibitor / Unkown
HY-173033 MI-883 99.57% Unkown
HY-180888 Lck-IN-5 Inhibitor 98.09% Unkown
HY-183912 PY-4Car2 Inhibitor / Unkown
HY-156199 o-Cresol sulfate 98.13% Unkown
HY-70037AS Cinacalcet-d3 hydrochloride Agonist 97.63% Unkown
HY-185002 BCMA CAR mRNA / Unkown
HY-117774 AHR-2244 hydrochloride / Unkown
HY-135601 Cinacalcet metabolite M4 / Unkown
HY-139678 SC13 / Unkown
HY-15106 SB-423557 Antagonist / Unkown
HY-153085 CD19 CAR circRNA / Unkown
HY-155295 Z-CITCO Agonist / Unkown
HY-160151 TP1L / Unkown
HY-174418 NM600 / Unkown
HY-70037S Cinacalcet-d3 Agonist / Unkown
HY-B0349S Meclizine-d8 / Unkown
HY-B1380A Carisoprodol/BSA / Unkown
HY-D2620 CAR-2 Inducer / Unkown
HY-P10417 RTDLDSLRTYTL Inhibitor / Unkown
HY-P10417B RTDLDSLRTYTL TFA Inhibitor / Unkown
HY-RS01905 Car1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01906 Car1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01907 Car12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01908 Car12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01909 Car2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01910 Car2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01911 Car4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01912 Car4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01913 Car9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01914 Car9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01934 CARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W015026R Isobutylparaben (Standard) / Unkown
HY-W015026S Isobutylparaben-d4 98.5% Unkown
HY-W709413 Panaxytriol / Unkown
HY-W722556 5α-Androstan-3α-ol / Unkown
HY-157288 (R)-Phe-A110/B319 / Unkown
HY-182543 NPS-467 Activator / Unkown
HY-RS22414 Cars2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28937 Cars2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W653978 Cinacalcet-d4 hydrochloride Agonist / Unkown
Bioactive MoleculesInhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990245 Anti-Mouse FAP Antibody (73.3) Inhibitor 95.00% Unkown
HY-P990870 Anti-CD19 Antibody (4G7) Inhibitor 98% Unkown
HY-P992178 ALLO-647 / Unkown
HY-P992338 CT-1119 Inhibitor / Unkown