RBM6 - RNA binding motif protein 6 Gene
Also Known as 3G2; g16; DEF3; DEF-3; HLC-11; NY-LU-12
生物種: Homo sapiens
About RBM6
This gene has 20 transcripts (splice variants), 215 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 33.9), lymph node (RPKM 31.2) and 25 other tissues.
Summary
Enables RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
RBM6 Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001167582.2 | NP_001161054.1 | RNA-binding protein 6 isoform 2 |
| NM_001349190.2 | NP_001336119.1 | RNA-binding protein 6 isoform 2 |
| NM_001349191.2 | NP_001336120.1 | RNA-binding protein 6 isoform 2 |
| NM_001349192.2 | NP_001336121.1 | RNA-binding protein 6 isoform 2 |
| NM_001349193.2 | NP_001336122.1 | RNA-binding protein 6 isoform 2 |
| NM_001349194.2 | NP_001336123.1 | RNA-binding protein 6 isoform 3 |
| NM_005777.3 | NP_005768.1 | RNA-binding protein 6 isoform 1 |
RBM6 Protein Structure
(458 - 529)
(658 - 733)
G-patch: G-patch domain (1051 - 1094)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1123 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
RNA-binding protein 6 |
|
RBM6 Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
RBM6 | P78332 | EEF1G | Homo sapiens | P26641-2 | 25416956 | |
|
Intra
|
RBM6 | P78332 | EEF1G | Homo sapiens | P26641-2 | 25416956 |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Tarp Syndrome |
|
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| Testis Seminoma |
|
|
| Lung Cancer |
|
|
| Noonan Syndrome 1 |
|
|
| Fanconi Anemia, Complementation Group A |
|
|
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Felis catus | RBM6 | VGNC | VGNC:69266 |
| Canis familiaris | RBM6 | VGNC | VGNC:45425 |
| Mus musculus | RBM6 | MGD | MGI:1338037 |
| Bos taurus | RBM6 | VGNC | VGNC:33807 |
| Rattus norvegicus | RBM6 | RGD | RGD:1560367 |
| Macaca mulatta | RBM6 | VGNC | VGNC:76683 |
| Others | RBM6 | NCBI |