Aco2 - aconitase 2, mitochondrial Gene

Enables aconitate hydratase activity. Predicted to be involved in isocitrate metabolic process and Tricarboxylic Acid Cycle. Predicted to act upstream of or within citrate metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in infantile cerebellar-retinal degeneration and optic atrophy 9. Orthologous to human ACO2 (aconitase 2). [provided by Alliance of Genome Resources, Apr 2022]