SLC2A8 - solute carrier family 2 member 8 Gene

Also Known as GLUT8; GLUTX1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 29988

About SLC2A8

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:127,397,169-127,407,898 (from NCBI)

This gene has 15 transcripts (splice variants), 261 orthologues and 13 paralogues. Broad expression in testis (RPKM 16.3), adrenal (RPKM 7.3) and 24 other tissues.

Summary

This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

SLC2A8 Products (3)

mRNA Protein Name
NM_001271711.2 NP_001258640.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 2
NM_001271712.2 NP_001258641.1 solute carrier family 2, facilitated glucose transporter member 8 isoform 3
NM_014580.5 NP_055395.2 solute carrier family 2, facilitated glucose transporter member 8 isoform 1

SLC2A8 Protein Structure

Sugar_tr

Sugar_tr: Sugar (and other) transporter (30 - 473)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 477 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 8

  • glucose transporter type 8

SLC2A8 抗体

製品番号 製品名 アプリケーション 反応性
HY-P811360 GLUT8/ DA41 Antibody WB, IHC-P, FC Human, Mouse, Rat

関連疾患

Diseases Alias
Type 1 Diabetes Mellitus 10
  • Diabetes Mellitus, Insulin-Dependent, 10

  • IDDM10

  • Insulin-Dependent Diabetes Mellitus 10

  • Diabetes, Mellitus, Insulin-Dependent, Susceptibility To, 10

  • T1D10

  • Diabetes, Mellitus, Insulin-Dependent 10

  • Diabetes Mellitus, Insulin-Dependent, Type 10

Arterial Tortuosity Syndrome
  • Arterial Tortuosity

  • Ats

  • ATORS

  • Tortuosity, Arterial, Syndrome

Hypoascorbemia
  • Scurvy

  • Ascorbic Acid Deficiency

  • Vitamin C Deficiency

  • Vitamin C, Inability To Synthesize

  • Deficiency Of Vitamin C

  • Scorbutus

  • Vitamin C

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus SLC2A8 VGNC VGNC:34803
Rattus norvegicus SLC2A8 RGD RGD:620611
Mus musculus SLC2A8 MGD MGI:1860103
Felis catus SLC2A8 VGNC VGNC:65306
Canis familiaris SLC2A8 VGNC VGNC:46344
Macaca mulatta SLC2A8 VGNC VGNC:77470
Others SLC2A8 NCBI