Dkkl1 - dickkopf-like 1 Gene
Also Known as SGY; SGY1; mSgy; SGY-1; Soggy
生物種: Mus musculus
Summary
Predicted to enable co-receptor binding activity and receptor antagonist activity. Involved in negative regulation of testosterone biosynthetic process; penetration of zona pellucida; and positive regulation of apoptotic process. Acts upstream of or within positive regulation of fat cell differentiation. Located in acrosomal vesicle. Is expressed in several structures, including extraembryonic component and reproductive system. Orthologous to human DKKL1 (dickkopf like acrosomal protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Dkkl1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_015789.3 | NP_056604.2 | dickkopf-like protein 1 precursor |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
19176879 | MGI |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| acts upstream of or within canonical Wnt signaling pathway |
IDA
IDA: Inferred from direct assay
|
29715368 | MGI |
| involved in negative regulation of testosterone biosynthetic process |
IMP
IMP: Inferred from mutant phenotype
|
18818293 | MGI |
| involved in penetration of zona pellucida |
IMP
IMP: Inferred from mutant phenotype
|
19596312 | MGI |
| involved in positive regulation of apoptotic process |
IMP
IMP: Inferred from mutant phenotype
|
18818293 | MGI |
| acts upstream of or within positive regulation of fat cell differentiation |
IDA
IDA: Inferred from direct assay
|
12055200 | MGI |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in acrosomal vesicle |
IDA
IDA: Inferred from direct assay
|
15892050 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
dickkopf-like protein 1 |
|