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MRTO4 - MRT4 homolog, ribosome maturation factor Gene

Also Known as MRT4; C1orf33; dJ657E11.4

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 51154

About MRTO4

This gene has 3 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in appendix (RPKM 7.6), lymph node (RPKM 7.5) and 25 other tissues.

Summary

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]

MRTO4 Products (1)

mRNA	Protein	Name
NM_016183.4	NP_057267.2	mRNA turnover protein 4 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	21044950	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MRTO4 Protein Structure

Ribosomal_L10

0
100
200
239 a.a.

Protein Preferred Names	Protein Names
mRNA turnover protein 4 homolog	60S acidic ribosomal protein PO

MRTO4 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	MRTO4	Q9UKD2	TERF2IP	Homo sapiens	Q9NYB0	Pull Down	21044950
Intra	MRTO4	Q9UKD2	TERF2IP	Homo sapiens	Q9NYB0	BiFC	21044950

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MRTO4 Proteins

製品番号	製品名	アクセッション番号	純度
HY-P75465	C1orf33/MRTO4 Protein, Human (His)	Q9UKD2 (M1-D239)	≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases	Alias
Branchiootorenal Syndrome 1	Melnick-Fraser Syndrome BOR1 Branchiootorenal Dysplasia Branchiootorenal Syndrome 1, With Or Without Cataracts Bor Syndrome 1 Branchiootorenal Dysplasia 1 Branchio-Oto-Renal Dysplasia 1 Branchio-Oto-Renal Syndrome Type 1 Branchiootorenal Syndrome, With/Without Cataract, Type 1 Branchio-Oto-Renal Syndrome
Shwachman-Diamond Syndrome 1	Shwachman-Diamond Syndrome Shwachman Syndrome Shwachman-Bodian-Diamond Syndrome Sds Pancreatic Insufficiency And Bone Marrow Dysfunction Shwachman-Bodian Syndrome SDS1 Lipomatosis Of Pancreas, Congenital Congenital Lipomatosis Of Pancreas Shwachman-Diamond Type Metaphyseal Dysplasia Metaphyseal Chondrodysplasia, Shwachman Type Shwachman-Diamond-Oski Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS08695	MRTO4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20992	Mrto4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27509	Mrto4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Mus musculus	MRTO4	MGD	MGI:1917152
Bos taurus	MRTO4	VGNC	VGNC:31680
Felis catus	MRTO4	VGNC	VGNC:63629
Canis familiaris	MRTO4	VGNC	VGNC:84430
Rattus norvegicus	MRTO4	RGD	RGD:1311709
Others	MRTO4	NCBI