Smpd2 - sphingomyelin phosphodiesterase 2 Gene

Also Known as nSMase

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 83537

Summary

Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process; intracellular signal transduction; and response to mechanical stimulus. Located in caveola. Orthologous to human SMPD2 (sphingomyelin phosphodiesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

Smpd2 Products (1)

mRNA Protein Name
NM_031360.2 NP_112650.1 sphingomyelin phosphodiesterase 2
Molecular Function GO Annotation Evidence 参考文献 由来
enables sphingomyelin phosphodiesterase activity IDA
IDA: Inferred from direct assay
10832103 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in ceramide biosynthetic process IDA
IDA: Inferred from direct assay
12473648 RGD
involved in intracellular signal transduction IMP
IMP: Inferred from mutant phenotype
12473648 RGD
involved in response to mechanical stimulus IMP
IMP: Inferred from mutant phenotype
12473648 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in caveola IDA
IDA: Inferred from direct assay
12473648 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sphingomyelin phosphodiesterase 2

  • N-SMase

  • lyso-PAF-PLC

  • lyso-platelet-activating factor-phospholipase C

  • neutral sphingomyelinase

  • sphingomyelin phosphodiesterase 2, neutral membrane

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Smpd2 NCBI NCBI:6610