OPALIN - oligodendrocytic myelin paranodal and inner loop protein Gene

Also Known as TMP10; HTMP10; TMEM10

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 93377

About OPALIN

Cytogenetic location: 10q24.1 Genomic coordinates (GRCh38): 10:96,343,221-96,359,002 (from NCBI)

This gene has 6 transcripts (splice variants) and 91 orthologues. Restricted expression toward brain (RPKM 29.7).

Summary

Predicted to be involved in regulation of oligodendrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

OPALIN Products (10)

mRNA Protein Name
NM_001040102.3 NP_001035191.1 opalin isoform b
NM_001040103.3 NP_001035192.1 opalin isoform c
NM_001284320.2 NP_001271249.1 opalin isoform d
NM_001284321.2 NP_001271250.1 opalin isoform e
NM_001284322.2 NP_001271251.1 opalin isoform c
NM_001284323.2 NP_001271252.1 opalin isoform c
NM_001284324.2 NP_001271253.1 opalin isoform c
NM_001284326.2 NP_001271255.1 opalin isoform f
NM_001284327.2 NP_001271256.1 opalin isoform f
NM_033207.5 NP_149984.1 opalin isoform a
Protein Preferred Names Protein Names

opalin

  • transmembrane protein 10

関連疾患

Diseases Alias
Fucosidosis

  • Alpha-L-Fucosidase Deficiency

  • Fucosidase Deficiency Disease

  • A-Fucosidase Deficiency

  • Alpha Fucosidase Deficiency

  • Lysosomal Storage Disease Caused By Defective Alpha-L-Fucosidase With Accumulation Of Fucose In The Tissues

  • Alpha-Fucosidase Deficiency

  • Fucosidase Deficiency

  • FUCA1D
Multiple Sclerosis

  • MS

  • Multiple Sclerosis, Susceptibility To

  • Disseminated Sclerosis

  • Multiple Sclerosis, Disease Progression, Modifier Of

  • Insular Sclerosis

  • Multiple Sclerosis Modifier Of Disease Progression

  • Multiple Sclerosis, Susceptibility To 1

  • Multiple Sclerosis, Susceptibility To, 1

  • Multiple Sclerosis 1

  • Generalized Multiple Sclerosis

  • Multiple Sclerosis Variant

  • Multiple Sclerosis Susceptibility To

  • Cerebrospinal Sclerosis

  • Generalised Multiple Sclerosis

  • Ms - [Multiple Sclerosis]

  • Disseminated Cerebrospinal Sclerosis

  • Disseminated Multiple Sclerosis

  • Disseminated Nervous System Myelosclerosis

  • Multiple Cerebrospinal Sclerosis

  • Multiple Combined Sclerosis

  • Multiple Sclerosis Generalised

  • Disseminated Brain Sclerosis

  • Disseminated Spinal Sclerosis

  • Insular Brain Sclerosis

  • Miliary Brain Sclerosis

  • Multiple Combined Sclerosis Of Spinal Cord

  • Multiple Ascending Sclerosis

  • Multiple Brain Sclerosis

  • Multiple Sclerosis Of Brain Stem

  • Multiple Sclerosis Of The Brain Stem

  • Multiple Sclerosis Of Cord

  • Sclérose En Plaques

  • Plaque Sclerosis

  • Multiple Sclerosis Of The Spinal Cord
Pelizaeus-Merzbacher Disease

  • PMD

  • HLD1

  • Pelizaeus-Merzbacher Brain Sclerosis

  • Leukodystrophy, Hypomyelinating, 1

  • Diffuse Familial Brain Sclerosis

  • Pelizaeus Merzbacher Brain Sclerosis

  • Sudanophilic Leukodystrophy, Paelizeus-Merzbacher Type

  • Cockayne-Pelizaeus-Merzbacher Disease

  • Hypomyelinating Leukodystrophy 1

  • Leukodystrophy, Sudanophilic

  • Pelizaeus Merzbacher Disease

  • Hypomyelinating Leukodystrophy, 1

  • Sudanophilic Leukodystrophy

  • Pelizaeus-Merzbacher Disease, Connatal Form

  • Connatal Pmd

  • Pelizaeus-Merzbacher Disease Type Ii

  • Severe Pmd

  • Null Syndrome

  • Plp1 Null Syndrome

  • Pelizaeus-Merzbacher Disease, Null Syndrome

  • Brain Sclerosis Diffuse Familial

  • Sudanophilic Leukodystrophy Paelizeus-Merzbacher Type

  • Leukodystrophy Hypomyelinating 1

  • Diffuse Cerebral Sclerosis Of Schilder
Hypomyelinating Leukodystrophy

  • Hld

  • Leukodystrophy, Hypomyelinating
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09791 OPALIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19798 Opalin Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26294 Opalin Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris OPALIN VGNC VGNC:44127
Bos taurus OPALIN VGNC VGNC:32434
Rattus norvegicus OPALIN RGD RGD:1307776
Macaca mulatta OPALIN VGNC VGNC:75443
Mus musculus OPALIN MGD MGI:2657025
Others OPALIN NCBI