Hsp90-IN-43
Hsp90-IN-43 (Compound 12) is a Hsp90-TPR2A interaction inhibitor with an IC50 of 360 nM and a Kd of 928 nM. Hsp90-IN-43 effectively inhibits the proliferation of BT474 cells. Hsp90-IN-43 can be used for the study of breast cancer.
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- CAS 番号: 164520-05-2
- 分子式: C14H13N5O2
- 分子量:283.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
0.9 μM
Compound: 286e
|
Antiproliferative activity against human BT-474 cells assessed as inhibition of cell growth
Antiproliferative activity against human BT-474 cells assessed as inhibition of cell growth
|
[PMID: 28851503] |
化学情報
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CAS 番号 164520-05-2
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分子量 283.29
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分子式 C14H13N5O2
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SMILES
O=C1N=C2C(C(N1C)=O)=NC(C3=CC=CC=C3)=NN2CC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)