m-PEG750-OH
Based on 1 Customer Validation
m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 9004-74-4
- 分子量:750 (Average)
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
m-PEG-OH can be used to encapsulate anticancer drugs. Hydrophobic anticancer agent Paclitaxel (HY-B0015) encapsulated in micelles exhibits stronger cancer cell-killing activity than free Paclitaxel. In addition, it preferentially accumulates in tumor tissues and shows only limited distribution in healthy organs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 9004-74-4
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性状 Oil
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分子量 750 (Average)
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Color White to off-white
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SMILES
COCCOCCO.[n]
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別名
mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 16.67 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Riccio G, et al. Monogalactosyldiacylglycerol and Sulfolipid Synthesis in Microalgae. Mar Drugs. 2020;18(5):237. Published 2020 May 1. [Content Brief]
[2]. Lee AL, et al. The use of cholesterol-containing biodegradable block copolymers to exploit hydrophobic interactions for the delivery of anticancer drugs. Biomaterials. 2012;33(6):1921-1928. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)