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COX-2-IN-51

COX-2-IN-51 (E25) is a potent COX-2 inhibitor, with an IC50 of 70.7 nM. COX-2-IN-51 significantly inhibits LPS-induced release of NO and PGE2, expression of COX-2 and iNOS, and activation of NF-κB pathway. COX-2-IN-51 exhibits anti-inflammatory and analgesic effects in diverse murine models through inhibiting NF-κB pathway. COX-2-IN-51 has lower gastrointestinal side effects than Indomethacin (HY-14397).

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  • CAS No.: 3064260-49-4
  • 화학식: C23H18F4O3S
  • 분자량:450.45
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • COX-2-IN-51 Chemical Structure
    COX-2-IN-51 Chemical Structure
CAS No.: 3064260-49-4
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    COX-2-IN-51 Chemical Structure
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  • COX-2-IN-51