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Cat. No.: HY-17609C

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Difelikefalin acetate

(Synonyms: CR-845 acetate; FE-202845 acetate)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

Difelikefalin (CR-845; FE-202845) acetate is a peripherally restricted and selective agonist of kappa opioid receptor (KOR). Difelikefalin acetate produces anti-inflammatory effects and has the potential in modulating pruritus in conditions such as chronic kidney disease.

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CAS No.: 2803411-76-7
화학식: C₃₈H₅₇N₇O₈
분자량:739.90

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Difelikefalin acetate Chemical Structure

CAS No.: 2803411-76-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Opioid Receptor Isoforms :

Chemical Information

CAS No. 2803411-76-7
분자량 739.90
화학식 C₃₈H₅₇N₇O₈
SMILES

CC(O)=O.O=C(C1(N)CCN(C([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)CC1)O
Synonyms

CR-845 acetate; FE-202845 acetate
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Cell

In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons. [Abstract]

2025 Dec 24;188(26):7547-7570.e45 PMID: 41406962

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Steven Fishbane, et al. Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients. Kidney Int Rep. 2020 Jan 28;5(5):600-610. [Content Brief]

[2]. Steven Fishbane, et al. A Phase 3 Trial of Difelikefalin in Hemodialysis Patients With Pruritus. N Engl J Med. 2020 Jan 16;382(3):222-232. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Difelikefalin acetate

1 Cited Publications

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Chemical Information
Publications (1)
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Difelikefalin acetate

Publications Citing Use of MedChemExpress (MCE) Difelikefalin acetate

All Opioid Receptor Isoforms

Biological Activity

Chemical Information

Publications (1)

순도&문서

References

Calculators

Help & FAQs

Difelikefalin acetate Related Classifications

HY-17609C Related Classifications