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Cat. No.: HY-N1455

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Falcarinol

(Synonyms: Panaxynol; Carotatoxin)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 99.83%
CAS No.: 21852-80-2
화학식: C₁₇H₂₄O
분자량:244.37

보관:

Solution, -20°C, protect from light, 2 years

Falcarinol Chemical Structure

CAS No.: 21852-80-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
Publications (1)
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Biological Activity

제품 설명

Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis^[1]. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

All HSP Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Hepatocyte	IC₅₀	>100 μM Compound: 20	Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes Inhibitory activity against D-GalN-induced cytotoxicity in rat hepatocytes	[PMID: 9873511]

In Vitro

Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 21852-80-2
Appearance Liquid
분자량 244.37
화학식 C₁₇H₂₄O
Color Colorless to light yellow
SMILES

C=C[C@@H](O)C#CC#CC/C=C\CCCCCCC
Synonyms

Panaxynol; Carotatoxin
Structure Classification
- Others
Initial Source
- Plants
- Umbelliferae
선적

Room temperature in continental US; may vary elsewhere.
보관

Solution, -20°C, protect from light, 2 years

Publications (1)

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Phytomedicine

Bruceantin inhibits the c-Myc/RL27A axis to suppress tumor progression in hepatocellular carcinoma. [Abstract]

2026 Jan:150:157740. PMID: 41477978

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Falcarinol

1 Cited Publications

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
Publications (1)
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Falcarinol

Publications Citing Use of MedChemExpress (MCE) Falcarinol

All HSP Isoforms

Biological Activity

Chemical Information

Publications (1)

순도&문서

References

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Falcarinol Related Classifications

HY-N1455 Related Classifications