Cirbp - cold inducible RNA binding protein Gene

Also Known as Cirp

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12696

Summary

Enables poly(U) RNA binding activity and translation repressor activity. Involved in stress granule assembly. Acts upstream of or within cellular response to cold; negative regulation of cell growth; and regulation of cell cycle G1/S phase transition. Located in cytoplasmic stress granule and nucleoplasm. Is expressed in several structures, including brain and retina. Orthologous to human CIRBP (cold inducible RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Cirbp Products (6)

mRNA Protein Name
NM_001379421.1 NP_001366350.1 cold-inducible RNA-binding protein isoform 2
NM_001379422.1 NP_001366351.1 cold-inducible RNA-binding protein isoform 1
NM_001379423.1 NP_001366352.1 cold-inducible RNA-binding protein isoform 3
NM_001379424.1 NP_001366353.1 cold-inducible RNA-binding protein isoform 1
NM_001379425.1 NP_001366354.1 cold-inducible RNA-binding protein isoform 1
NM_007705.3 NP_031731.1 cold-inducible RNA-binding protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
9151692 MGI
enables poly(U) RNA binding IDA
IDA: Inferred from direct assay
9151692 MGI
enables translation repressor activity IDA
IDA: Inferred from direct assay
17967451 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to cold IDA
IDA: Inferred from direct assay
9151692 MGI
acts upstream of or within negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
9151692 MGI
acts upstream of or within regulation of cell cycle G1/S phase transition IDA
IDA: Inferred from direct assay
9151692 MGI
involved in stress granule assembly IDA
IDA: Inferred from direct assay
17967451 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17967451 MGI
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
17967451 MGI
located in nucleoplasm IDA
IDA: Inferred from direct assay
9151692 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17967451 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cold-inducible RNA-binding protein

  • A18 hnRNP

  • glycine-rich RNA-binding protein CIRP

Recombinant Cirbp Proteins

Cat. No. 상품명 Accession Purity
HY-P72145 CIRBP Protein, Mouse (His) P60824 (M1-E172) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-125972 zr17-2 Activator 98.01% Unkown
HY-RS02721 CIRBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180496 (S)-NSC 121182 / Unkown
HY-RS17760 Cirbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24227 Cirbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cirbp NCBI NCBI:1153