CIRBP - cold inducible RNA binding protein Gene

Homo sapiens

Also known as CIRP

Gene ID: 1153 | Gene type: protein coding

About CIRBP

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,269,332-1,274,880 (from NCBI)

This gene has 46 transcripts (splice variants), 163 orthologues and 36 paralogues. Ubiquitous expression in ovary (RPKM 151.3), endometrium (RPKM 107.4) and 25 other tissues.

Summary

Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CIRBP Products(3)

mRNA	Protein	Name
NM_001280.3	NP_001271.1	cold-inducible RNA-binding protein isoform 1
NM_001300815.2	NP_001287744.1	cold-inducible RNA-binding protein isoform 2
NM_001300829.2	NP_001287758.1	cold-inducible RNA-binding protein isoform 3

CIRBP Protein Structure

RRM_1

0
100
172 a.a.

Protein Preferred Names

Protein Names

cold-inducible RNA-binding protein

A18 hnRNP

Recombinant CIRBP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76261	CIRBP Protein, Human (His)	Q14011 (M1-E172)	≥95%
HY-P76261A	CIRBP Protein, Human (N-C-His)	Q14011 (M1-E172)	≥95%

Related Diseases

Diseases

Alias

Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism	Undescended Testicle
Undescended Testis	Cryptorchism
Undescended Testicles	CRYPTO
Impaired Testicular Descent	Cryptosporidiosis
Retained Testis	Unilateral Cryptorchidism
Unilateral Undescended Testis	Nondescent Unilateral Testicle
Unilateral Cryptorchism	Ectopic Testis, Unilateral
Bilateral Cryptorchidism	Bilateral Cryptorchism
Bilateral Nondescent Testicle	Bilateral Undescended Testes
Bilateral Ectopic Testes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02721	CIRBP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CIRBP	RGD	RGD:620756
Mus musculus	CIRBP	MGD	MGI:893588
Macaca mulatta	CIRBP	VGNC	VGNC:81371
Felis catus	CIRBP	VGNC	VGNC:60908
Bos taurus	CIRBP	VGNC	VGNC:52752
Canis familiaris	CIRBP	VGNC	VGNC:54590
Others	CIRBP	NCBI

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