Gnal - guanine nucleotide binding protein, alpha stimulating, olfactory type Gene

Also Known as Golf; Hg1o; Gna10; Galphaolf; 2610011C15Rik; 9630020G10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14680

Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Acts upstream of or within several processes, including activation of Adenylate Cyclase activity; adenylate cyclase-activating Dopamine Receptor signaling pathway; and response to caffeine. Predicted to be part of heterotrimeric G-protein complex. Is expressed in nervous system; sensory organ; and spleen. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Gnal Products (2)

mRNA Protein Name
NM_010307.3 NP_034437.1 guanine nucleotide-binding protein G(olf) subunit alpha isoform 1
NM_177137.5 NP_796111.2 guanine nucleotide-binding protein G(olf) subunit alpha isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein activity IDA
IDA: Inferred from direct assay
21467038 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within activation of adenylate cyclase activity IDA
IDA: Inferred from direct assay
12488442 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
2499043 MGI
acts upstream of or within adenylate cyclase-activating dopamine receptor signaling pathway IGI
IGI: Inferred from genetic interaction
17194762 MGI
acts upstream of or within response to amphetamine IMP
IMP: Inferred from mutant phenotype
11404425 MGI
acts upstream of or within response to caffeine IMP
IMP: Inferred from mutant phenotype
11404425 MGI
acts upstream of or within sensory perception of smell IMP
IMP: Inferred from mutant phenotype
9459443 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(olf) subunit alpha

  • G alpha 10

  • adenylate cyclase-stimulating G alpha protein, olfactory type

  • guanine nucleotide binding protein, alpha 10

  • heterotrimeric guanine nucleotide-binding protein 1o

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS05537 GNAL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17331 Gnal Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23786 Gnal Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnal NCBI NCBI:2774