Atp6v1a - ATPase H+ transporting V1 subunit A Gene

Also Known as Atp6v1a1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 685232

Summary

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in cellular iron ion homeostasis; cellular response to increased oxygen levels; and proton transmembrane transport. Predicted to be located in several cellular components, including apical plasma membrane; microvillus; and secretory granule. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Orthologous to human ATP6V1A (ATPase H+ transporting V1 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1a Products (1)

mRNA Protein Name
NM_001108318.2 NP_001101788.1 V-type proton ATPase catalytic subunit A

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32165585 RGD
Cellular Component GO Annotation Evidence References Source
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: Inferred from Experiment
32165585 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: Inferred from direct assay
32165585 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase catalytic subunit A

  • ATPase, H+ transporting, lysosomal V1 subunit A

Atp6v1a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Atp6v1a D4A133 q5zww6_legph Legionella pneumophila subsp. pneumophila Q5ZWW6
SLCA
32165585
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-128892 EN6 Activator 99.32% Unkown
HY-RS29446 ATP6V1A Monkey Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01223 ATP6V1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18574 Atp6v1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25058 Atp6v1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v1a NCBI NCBI:523