JAK-IN-27

JAK-IN-27 (compound 1) is an orally active and potent JAKS family kinase inhibitor with IC50s of 3.0 nM (TYK2), 7.7 nM (JAK1), 629.6 nM (JAK3), respectively. JAK-IN-27 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=23.7 nM).

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  • CAS No.: 2673176-36-6
  • 화학식: C20H21F2N7O
  • 분자량:413.42
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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